10 results
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
stored red blood cells ... • chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Diagnosis and workup ... the diagnostic workup ... - Progressive amnesia ... MNCD #Dementia #Differential ... #Subtypes #Classification
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Algorithm • Sickle cells ... #Differential # ... Diagnosis #Algorithm #workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... abnormal under the microscope ... abnormal under a microscope ... Workup: • Complete ... blood count with differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... (LP) tumour B cells ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... Diagnosis #NonHodgkin #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
SvO2 → Low PaO2 ANEMIC ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
Vegetations may be microscopic ... embolize • Cannot differentiate ... Inflammatory cells ... absent How can we differentiate ... Marantic #diagnosis #pathophysiology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
Anemia of Hospitalization ... - Pathophysiology ... phlebotomy/ blood work ... Hospitalization #causes #pathophysiology ... #differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential ... #typea #typeb #classification