24 results
diagnosis hematology differential oncology management causes algorithm clinical leukemia photo rheumatology activetb cll latenttb lymphocytic syndrome tb treatment tuberculosis vasculitis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... Autoimmunity • Chronic ... DDX - Other causes ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic ... Reed-Sternberg Cells ... Algorithm #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Diagnosis Algorithm Infection ... Myeloproliferative Disorder • Chronic ... pancytopenia, blast cells ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Scoring system: DDX ... Contamination, colitis DDX ... leukemia #CLL #Chronic
Important organisms in Chronic Granulomatous Disease (CGD): - Staph aureus - Serratia marcescens - Burkholderia cepacia
Important organisms in Chronic ... febrilepodcast.com] #CGD #Chronic ... Granulomatous #Disease #infections ... #differential #ddx ... #diagnosis #microbiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... plaques) AML Dx ... #Leukemia #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
similarly to mast cells ... Disorders: • Chronic ... Diabetes/DKA Infections ... : • helminth infections ... Diagnosis #causes #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Macrocytic anemia DDX ... Marrow Failure • Chronic ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... • Silicosis • Chronic ... disease • DM DDX ... Langerhans giant cells ... malignancy, and chronic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... and thymoma DDX ... number of CD34+ cells ... Anemia #oncology #hematology
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