26 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... risk-stratification • Risks: infection ... acute leukemia Management ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... and thymoma DDX ... Anemia #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... or basket cells ... Scoring system: DDX ... Contamination, colitis DDX ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Mean age at Dx ... petechiae) • Frequent infections ... Macrocytic anemia DDX ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Dx? ... When considering infections ... bacillus cause selsis ... C. canimorsus infection ... Canimorsus #Skin #Rash #dermatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... macrophages and T cells ... disease • DM DDX ... Langerhans giant cells ... TB #Diagnosis #Management
Cyclosporiasis - Diagnosis and Management Summary
Pathogen: 
 • Cyclospora cayetanensis
 • Foodborne, waterbone, and soil-transmitted.
 •
Diagnosis and Management ... transmission as zoonotic infection ... Established via stool microscopy ... cayetanensis #diagnosis #management ... #treatment #microbiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... plaques) AML Dx ... #Leukemia #Hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... macrophages and T cells ... disease • DM DDX ... Langerhans giant cells ... TB #Diagnosis #Management