10 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... = funny-shaped cells ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... diagnosis #hematology #oncology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Differential Diagnosis Algorithm ... Redistribution/ Shift into cells ... ), Hungry bone syndrome ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... Aplastic #Anemia #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Release from blast cells ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... .2>5 red blood cells ... #Algorithm #differential ... #nephrology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
-6 activates T cells ... Cytokine Activation Syndrome ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... kidney tubular cells ... Differential #Diagnosis #Management ... causes #treatment #nephrology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... aggregate) of CD4 T cells ... , B cells, and plasma ... cells around salivary ... lubricants • Pharmacologic
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... apical membrane of cells ... #diagnosis #nephrology ... #management #pathophysiology