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hematology differential oncology mds myelodysplastic aplastic cardiology classification disease elevatedmcv endocarditis fever hematuria hemolytic hodgkins infectiousdiseases lymphoma macrocytic macrocytosis potts
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age • 22 and 45 cases ... Peripheral Smear ... Peripheral blood smear ... #Syndromes #diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal ... Blood Smear • ... Dysplastic • Myelodysplastic ... #Algorithm #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... old, ~10,000 new cases ... cytopenias (usually anemia ... BrighamChiefs #Myelodysplastic
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Algorithm Hereditary ... Peripheral blood smear ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Algorithm Red ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... #Algorithm #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... • Hypocellular myelodysplastic ... oncology #hematology #diagnosis ... #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Tuberculosis - Diagnosis ... and Management ... extrapulmonary cases ... Detection of AFB by smear ... microscopy Management
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
positive in 90% of IE cases ... Septic Emboli Cause ... Leukocytosis, anemia ... Treat underlying cause ... #management #cardiology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Weight loss • Anemia ... Immune hemolytic anemia ... Lymphoma (90-95% of cases ... hematology #oncology #management
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... falciparum: Most cases ... chest film; blood-smear ... dipstick test, microscopic ... examination, culture
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