34 results
differential rheumatology management oncology algorithm causes dermatology hepatology liver anemia classification hemophagocytic hlh injury leukemia lymphohistiocytosis skin treatment vasculitis acquired
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... criteria for 1) hematologic ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
transfusion • Target cells ... anemia • Sickle cells ... alcoholism • Burr cells ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
and Associated Syndromes ... Atrophic erminal center ... Diffuse plasma cells ... Pathogenesis "IL6 syndrome ... #Variants #Diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... thrombocythemia), Autoimmune disease ... adsorption onto cancer ... cells (and subsequent ... #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
temporalis (giant-cell ... granulomatosis - microscopic ... Vasculitis #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... can indicate disease
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... of glomerular disease ... necrosis (Sickle cell ... BPH • Prostate cancer
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Vasculitides: Giant Cell ... arteritis, Cogan's Syndrome ... Other Causes: Cancer ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... B-LNH), solid cancers ... • Autoimmune diseases ... Adult-onset Still disease
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