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Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework Basophils ... the total white blood ... cell count Basophils ... similarly to mast cells
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... revealed 25% plasma cells ... Clinical #HONC #Derm ... Leukemia #Smear #NEJM
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... anemia Sickled red cells ... disease Bite cells ... , Thalassemia Basophilic ... #Peripheral #Blood
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Leukocytosis: The term ... eosinophils, & basophils ... defined as white blood ... in peripheral blood ... NEUTROPHILS #WCC #BASOPHILS
Morphologic Findings in Red Blood Cells
Basophilic stippling - Small blue dots in red cells, due to
Findings in Red Blood ... Cells Basophilic ... and grayer than basophilic ... ) - Red blood cells ... ) - Red blood cells
African Trypanosomiasis - The examination was notable for the two erythematous lesions, each measuring 3 to
A peripheral-blood ... B) #Clinical #Derm ... TrypanosomaBrucei #NEJM
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
point to blister cells ... These cells are ... precursors of helmet cells ... The photo on the ... Path #BloodSmear #Blood
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
used on a long-term ... convoluted tubule cells ... , principal cells ... and intercalated cells ... NephronRemodeling #NEJM
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
point to helmet cells ... seen in the left photo ... cell, 2 blister cells ... In the right photo ... Path #BloodSmear #Blood
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... cells, aka normoblasts ... other nucleated cells ... proerythroblast – basophilic ... #BloodSmear #Blood