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differential causes hematology multiple oncology anemia castlemans cell clinical disease elevatedmcv fractures fragility hepatitis hepatology injury liver macrocytic macrocytosis management
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Pathologic / Fragility ... - Differential Diagnosis ... Algorithm Tumours ... - Skull/spine/Pelvis ... #Differential #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... #Algorithm #Causes
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... lymphoma, melanoma, myeloma ... #differential #diagnosis ... #algorithm #hepatology
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
characteristic of multiple myeloma ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... raindrop #multiple #myeloma
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... patients with EMD myeloma ... Diagnostic Evaluation ... IFE, FLC assay Pathology ... • Multiple myeloma
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