9 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
ringworm, was diagnosed ... #clinical #photo ... #NEJM #tinea #capitis ... #ringworm #derm
Disseminated Cutaneous Blastomycosis- A fungal culture of skin tissue was negative; however, a skin biopsy showed
staining confirmed a diagnosis ... #clinical #photo ... #derm #NEJM #cutaneous
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
characteristic of multiple myeloma ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... raindrop #multiple #myeloma
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Smear #Microscopy #NEJM
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
A diagnosis of pyoderma ... #clinical #photo ... #NEJM #pyoderma ... ulcerative #colitis #derm
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Diagnosis? ... patients with EMD myeloma ... Diagnostic Evaluation ... IFE, FLC assay Pathology ... • Multiple myeloma
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... #NEJM #clinical ... #photo #lichen # ... planus #derm #wickhams