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management oncology clinical dermatology differential hemeonc algorithm amyotrophic arterial canimorsus capnocytophaga cell embolism emergencies gangrenosum hemophagocytic hepatitis hepatology hlh injury
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... septic emboli) - Myxoma ... Venous #Arterial #pathophysiology ... #hematology #differential ... #diagnosis #vascular
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis of tumor cells ... #diagnosis #management ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... lymphoma, melanoma, myeloma ... #differential #diagnosis ... #algorithm #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... lateral sclerosis Pathophysiology ... - Microglial cells ... - Causes progressive ... Escorial criteria uses
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... three myeloid hematopoiesis ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... selsis after a ... underlying r.f as ... the key to the diagnosis ... #clinical #photo
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... patients with EMD myeloma ... IFE, FLC assay Pathology ... • Multiple myeloma ... #Workup #Hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Treat underlying cause ... Leukostasis: - Usually myeloid ... “big & sticky” cells ... Oncology #HemeOnc #Diagnosis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including lymphoma, myeloma ... cell lymphoma Pathophysiology ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
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