8 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... lymphoma, multiple myeloma ... #Management #treatment ... #hematology #differential
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel ... and Management ... Treatment: • Global ... IBS #Irritable #Bowel ... #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
limb ischemia, bowel ... organ damage • Treatment ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... urinary retention, bowel ... Leukostasis: - Usually myeloid ... “big & sticky” cells ... Oncology #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
patients with EMD myeloma ... IFE, FLC assay Pathology ... Bone marrow Treatment ... • Multiple myeloma ... #Workup #Hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including lymphoma, myeloma ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... agonists #TAFRO #diagnosis ... #management #rheumatology
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... neutrophils & T-cells ... Management of PG ... PG secondary treatment ... #PG #clinical #photo