12 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... thrombocytopenia, multiple ... criteria for 1) hematologic ... conditions - multiple ... cells NEJM Review
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Management Summary myelo ... = funny-shaped cells ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Formation • Multiple ... Myeloma Dysplastic ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... lymphocytes, plasma cells ... the mainstay of treatment ... the setting of multiple ... myeloma or AL amyloidosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... , mononeuritis multiplex ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Diagnosis #Management
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Diagnosis? ... , atrial myxoma, ... Churg-Strauss syndrome ... Multiple etiologic ... #clinical #photo
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Leukostasis: - Usually myeloid ... “big & sticky” cells ... → no immediate treatment ... Oncology #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
patients with EMD myeloma ... IFE, FLC assay Pathology ... Bone marrow Treatment ... • Multiple myeloma ... #Workup #Hematology