7 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... plasma clonal cell ... #Multiple #Myeloma
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
disease PLASMA CELL ... Diffuse plasma cells ... disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
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for Antenatal Diagnosis ... Fetal infection serology ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... Antenatal #Testing #Diagnosis
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Rickettsialpox Eschar ... Diagnosis? ... not endothelial cells ... rickettsia) Dx: serology ... rakari #clinical #photo
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... - Microglial cells ... are the immune cells ... between nerve cells ... Lateral #Sclerosis #neurology
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
characteristic of multiple myeloma ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... raindrop #multiple #myeloma
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
arises from plasma cells ... from the plasma cells ... monoclonal plasma cells ... clonal plasma cells ... IFE, FLC assay Pathology