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hematology management algorithm differential mds mgus monoclonal myelodysplastic radiology als amyotrophic anemia bone bony cell clinical elevatedmcv gammopathies gammopathy lateral
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... #Myeloma #Diagnosis ... #Management #oncology
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
- Differential Diagnosis ... adult tumours • Multiple ... Myeloma- most common ... #Orthopedics #Causes ... #Oncology #Radiology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... Management Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... treatment #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Formation • Multiple ... Myeloma Dysplastic ... Macrocytosis, Target Cells
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
progress to IgM multiple ... myeloma Non-IgM ... progression to multiple ... Significance #hematology #diagnosis ... #oncology
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
myeloma. ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... #myeloma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... -> AML: Blast crises ... Leukemia #Hematology #Oncology ... #Diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... - Microglial cells ... brainstem and multiple ... - Causes progressive ... Escorial criteria uses
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
skin that are caused ... , or all three myeloid ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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