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hematology management myelodysplastic syndrome autoinflammatory cell clinical e1 gammopathy mgus monoclonal myelodysplasia plasmacytoma radiology raindrop rheumatology significance skull solitary somatic
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... #Myeloma #Diagnosis ... #Management #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thrombocytopenia, multiple ... syndrome (MDS) ... hematologic conditions - multiple ... syndrome (MDS) ... cells NEJM Review
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome (MD ... Management Summary myelo ... = funny-shaped cells ... Myelodysplastic #Syndrome #MDS ... treatment #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
progress to IgM multiple ... myeloma Non-IgM ... progression to multiple ... Significance #hematology #diagnosis ... #oncology
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
myeloma. ... The diagnosis was ... clonal plasma cells ... #NEJM #clinical ... #myeloma
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... platelets) • MDS ... , or all three myeloid ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... patients with EMD myeloma ... IFE, FLC assay Pathology ... • Multiple myeloma ... #Plasmacytoma #Oncology
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