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diagnosis differential clinical causes management algorithm hematology smear dermatology pathophysiology nephrology rheumatology path treatment bloodsmear anemia hepatology microscopy secondary signs
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... anemia, Liver diseases ... Myelodysplastic syndrome ... , Liver diseases ... Hemolytic uremic syndrome
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... blood smears. ... to sickle cell disease ... thalassemia, and HbSC disease ... Path #BloodSmear #Blood
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myeloproliferative Disease ... cells, red blood ... cells - red blood ... cells, white blood
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... and Associated Syndromes ... • Hyalinizeä blood ... Diffuse plasma cells ... Pathogenesis "IL6 syndrome
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
point to blister cells ... These cells are ... precursors of helmet cells ... The photo on the ... Path #BloodSmear #Blood
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
point to helmet cells ... seen in the left photo ... cell, 2 blister cells ... In the right photo ... Path #BloodSmear #Blood
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
) - Two target cells ... seen in the left photo ... present in the left photo ... Target cells are ... Path #BloodSmear #Blood
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
The left photo also ... and the right photo ... nucleated red blood ... cells). ... Path #BloodSmear #Blood
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