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diagnosis differential causes hematology management smear bloodsmear frost gitelman path rheumatology uremic workup abg acid acidbase acidosis agglutinin algorithm amyloid
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... Myelodysplastic syndrome ... - Renal diseases ... Hemolytic uremic syndrome
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... thromboembolic disease ... Abnormalities: macrocytic anemia ... including peripheral blood ... NEJM Review: https
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #BloodSmear #Blood
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
blood smears. ... to sickle cell disease ... no significant anemia ... #Clinical #Path ... #BloodSmear #Blood
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... disease (30%): ... (75%): Anemia (
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
based on repeat clinic ... visits, Ambulatory blood ... multi-drug resistance) Renal ... Parenchymal Diseases ... HTN #Secondary #Nephrology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... cells (RBCs) at
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Dermatomyositis Clinical ... UA positive for blood ... kidney tubular cells ... of underlying disease ... causes #treatment #nephrology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Base Disorders - Blood ... D-lactate (short bowel syndrome ... failure (uremia ... restrictive lung disease ... Diagnosis #Summary #Nephrology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... can indicate disease ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Richter’s Syndrome
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