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diagnosis differential hematology treatment rheumatology algorithm clinical nephrology oncology causes renal anemia hepatology smear bloodsmear chronic classification dermatology endocrinology inflammatory
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... anemia, Liver diseases ... Myelodysplastic syndrome ... , Liver diseases ... Hemolytic uremic syndrome
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... blood smears. ... to sickle cell disease ... thalassemia, and HbSC disease ... Path #BloodSmear #Blood
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myeloproliferative Disease ... cells, red blood ... cells - red blood ... cells, white blood
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... Activation: Liver disease ... , Kidney Disease ... Pancreatitis, Blood ... - DiGeorge Syndrome
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... and Associated Syndromes ... • Hyalinizeä blood ... Diffuse plasma cells ... Pathogenesis "IL6 syndrome
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Campylobacter Clinical • Fever • Abdominal pain • Diarrhea (bloody stools) • Vomiting
• Diarrhea (bloody ... Guillain-Barré syndrome ... Management ... Antibiotics for severe disease ... Campylobacter #Diagnosis #Management
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Irritable bowel syndrome ... Systemic disease ... leukocytes and occult blood ... Malabsorption syndromes ... Chronic #Diarrhea #management
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... adsorption onto cancer cells ... vonWillebrand #Syndrome
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