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diagnosis hematology oncology causes differential algorithm clinical anemia management smear bloodsmear generalized mds myelodysplastic path pruritus secondary systemic treatment agglutinin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
or basket cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome ... workup #oncology #hematology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse bullous lesions (not shown). These
Leukemic skin Infiltrate ... Acute Myelogenous Leukemia ... cells. ... Images #Clinical #Photo ... #Dermatology #SkinRash
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... cells, red blood ... cells - red blood ... #diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... similarly to mast cells ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Diagnosis #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
/ Systemic == Blood ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... anemia • Sickle cells ... Hemolytic uremic syndrome ... #differential #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... result from low blood ... Anemia #oncology #hematology
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