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diagnosis clinical hematology oncology smear bloodsmear management mds myelodysplastic path amyloid asplenia autoinflammatory babesia babesiosis chronic derm e1 honc howell
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... aplasia • ITP ... • Richter’s Syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... : • Peripheral ... result from low blood
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... ) Peripheral ... • Aplastic Anemia ... Chronic Myelogenous Leukemia ... Cell Leukemia
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... Leukemia - Physical ... A peripheral-blood ... revealed 25% plasma cells ... #Smear #NEJM
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... confusion...A peripheral-blood ... Spur-cell anemia ... #NEJM #clinical ... #peripheral #blood
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... (12%) • giant cell ... including peripheral ... blood myeloid cells ... NEJM Review: https
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... cells on peripheral ... blood smears. ... no significant anemia ... Path #BloodSmear #Blood
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... Increased plasma cells ... and stocking" peripheral ... Diagnostic Testing Blood
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