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diagnosis clinical smear hematology oncology anemia bloodsmear path causes differential management algorithm amyloid amyloidosis antenatal aplastic asplenia autoinflammatory babesia bands
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... 🔬Tumor cells are ... Prolymphocytes #Smear #Peripheral ... Microscopy #Clinical #Blood
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
defined as white blood ... circulate freely in peripheral ... blood; The rest ... the margins of blood ... cell type in the peripheral
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... differential • Peripheral
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... or basket cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hereditary: • Peripheral ... blood smear + DAT ... History • Bite cells ... Deficiency • Sickle cells ... Infection mediated (Babesiosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... toxins: Malaria, Babesiosis ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral ... blood myeloid cells ... NEJM Review: https
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
confusion...A peripheral-blood ... resolve despite blood ... #NEJM #clinical ... spurcell #anemia #peripheral ... #blood #smear
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