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diagnosis chronic cll lymphocytic mds myelodysplastic treatment anemia aplastic autoinflammatory causes coagulation dic disseminated e1 hemeonc intravascular myelodysplasia rheumatology somatic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... including peripheral ... blood myeloid cells ... NEJM Review: https
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Diagnosis: • Peripheral ... lymphocytes, smudge cells ... characteristic • Peripheral ... #oncology #hematology ... hemeonc #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... D-Dimer: ↑ • Peripheral ... causes #treatment #management ... #hematology
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