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clinical diagnosis hematology bloodsmear oncology aplastic asplenia babesia babesiosis chronic cll coagulation dic disseminated howell howelljollybody intravascular jolly lymphocytic mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... -> AML: Blast crises ... - infiltrates (anemia ... smear: Blasts ... • Tumor lysis syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Smear: • Dysplastic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood smear •
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... in the right photo ... thalassemia, and leukemia ... #Clinical #Path
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... no significant anemia ... #Clinical #Path ... #BloodSmear #Blood
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #Smear #Schistocytes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ...

Causes of spherocyte ... and hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood

Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Sezary syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... ) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... D-Dimer: ↑ • Peripheral ... smear: Schistocytes ... #treatment #management
Babesiosis on Peripheral Smear 85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
Babesiosis on Peripheral ... IgG4 plasmacytic syndrome ... post exchange: blood ... lysis: fever, anemia ... ARDS and DIC, case
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