8 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... develop leukostasis syndrome ... - infiltrates (anemia ... smear: Blasts ... • Tumor lysis syndrome
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
In the right photo ... intravascular coagulation ... hemolytic- uremic syndromes ... #Clinical #Path ... #Smear #Schistocytes
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... in the right photo ... thalassemia, and leukemia ... #Clinical #Path
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... Smear: • Dysplastic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood smear
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... no significant anemia ... #Clinical #Path ... #BloodSmear #Blood
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Sezary syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... ) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... ABO incompatible blood ... D-Dimer: ↑ • Peripheral ... smear: Schistocytes ... causes #treatment #management