9 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... smear revealed ... 25% plasma cells ... #Smear #NEJM
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Pruritis after hot bath ... develop leukostasis syndrome ... smear: Blasts ... • Tumor lysis syndrome
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #SickleCells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... Smear: • Dysplastic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... in the right photo ... thalassemia, and leukemia ... #Clinical #Path
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #Smear #Schistocytes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... result from low blood ... hematology #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... ABO incompatible blood ... D-Dimer: ↑ • Peripheral ... smear: Schistocytes ... causes #treatment #management