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diagnosis bloodsmear clinical differential management rheumatology smear algorithm autoinflammatory chemistry dacrocytes e1 endocrinology hematology hepatology hypocalcemia interpretation leukemia lfts oncology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... Increased plasma cells ... Diagnostic Testing Blood ... Diagnostic imaging of liver
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
- Activation: Liver ... Formation: Hungy Bone Syndrome ... Pancreatitis, Blood ... Infiltrative: Amyloid ... - DiGeorge Syndrome
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
Dacrocytes (tear drop cells ... each of the above photos ... myelofibrosis, myeloid ... #Clinical #Path ... #BloodSmear #Blood
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #BloodSmear #Blood
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... as neoplasm or amyloid ... intestines, White blood ... cells Unconjugated ... • Gilbert's syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... Pruritis after hot bath ... develop leukostasis syndrome ... • Tumor lysis syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... PE, Pulmonary amyloidosis ... , PAH Skin: • ... vasculitis: 10%-16% Liver
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