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diagnosis hematology amyloid anemia aplastic autoinflammatory bloodsmear causes coagulation dic disseminated e1 intravascular oncology schistocytes sjogrens smear somatic treatment vacuoles
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... including peripheral blood ... NEJM Review: https ... Autoinflammatory #Somatic #rheumatology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Clinical Manifestations ... : • Nephrotic syndrome ... Diagnostic Testing Blood ... Diagnostic imaging of liver
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #BloodSmear #Blood
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... PE, Pulmonary amyloidosis ... vasculitis: 10%-16% Liver ... #Rheumatology # ... Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... DIC • Severe Liver ... causes #treatment #management ... #hematology
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