9 results
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #BloodSmear #Blood
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
Schistocytes can ... seen in the left photo ... In the right photo ... #Clinical #Path ... #BloodSmear #Blood
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... Pulmonary emboli • Schistocytes ... Hemolytic uremic syndrome ... #differential #hematology
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
The left photo also ... shows a schistocyte ... and the right photo ... #Clinical #Path ... #BloodSmear #Blood
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https ... Autoinflammatory #Somatic #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Tests • Liver ... Algorithm #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... Peripheral smear: Schistocytes ... , helmet cells ... studies - PBS: + Schistocytes ... DIC • Severe Liver
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Pruritis after hot bath ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... Pulmonary amyloidosis, PAH ... vasculitis: 10%-16% Liver ... #Rheumatology #