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clinical bloodsmear path diagnosis hematology anemia leukemia management mds myelodysplastic peripheral schistocytes agglutinin algorithm antenatal asplenia autoinflammatory babesia babesiosis blister
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... result from low blood ... #Anemia #oncology
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
point to blister cells ... These cells are ... The photo on the ... Path #BloodSmear #Blood ... #Smear #BlisterCells
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... smear revealed ... 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Causes • Anemia • Aplastic ... cells, red blood ... smear • Bone marrow ... diagnosis #hematology #oncology
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
) - Two target cells ... seen in the left photo ... present in the left photo ... Path #BloodSmear #Blood ... #Smear #Codocytes
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
point to helmet cells ... seen in the left photo ... In the right photo ... Path #BloodSmear #Blood ... #Smear #Helmet
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... blood smears. ... In the left photo ... Path #BloodSmear #Blood ... #Smear #SickleCells
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... = funny-shaped cells ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
The left photo also ... and the right photo ... nucleated red blood ... Path #BloodSmear #Blood ... #Smear #Polychromatophilia
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
Dacrocytes (tear drop cells ... each of the above photos ... Path #BloodSmear #Blood ... #Smear #Dacrocytes
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