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oncology hematology clinical path smear anemia antenatal aplastic asplenia chronic cll dermatology e1 howell howelljollybody jolly laboratory lymphocytic management mds
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... including peripheral blood ... myeloid cells ... NEJM Review: https ... #E1 #Xlinked #Autoinflammatory
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Hematology #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... Clinical #Path #BloodSmear ... #Blood #Smear #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... cells, red blood ... cells - red blood ... #diagnosis #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
dermatoses are autoinflammatory ... - Lupus - Leukemia ... cutis Diagnosis ... neutrophils in the blood ... #diagnosis #dermatology
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... result from low blood ... oncology #hematology #diagnosis
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral blood ... in the right photo ... thalassemia, and leukemia ... Clinical #Path #BloodSmear ... #Blood #Smear #
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