10 results
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
, these cells result ... shapes of red cells ... In the right photo ... hemolytic- uremic syndromes ... Clinical #Path #BloodSmear
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
Schistocytes can ... seen in the left photo ... In the right photo ... Clinical #Path #BloodSmear ... #HelmetCells #Schistocytes
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
The left photo also ... shows a schistocyte ... and the right photo ... to release red cells ... Clinical #Path #BloodSmear
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
enzyme, X-linked, Autoinflammatory ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https ... #E1 #Xlinked #Autoinflammatory
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... anemia • Sickle cells ... Pulmonary emboli • Schistocytes ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Etiology unknown: Autoinflammatory ... lower-extremity joints Diagnosis ... • A clinical diagnosis ... , breast bone, pelvis ... #Rheumatology #diagnosis
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
for Antenatal Diagnosis ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome ... Antenatal #Testing #Diagnosis
Babesiosis on Peripheral Smear
85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
IgG4 plasmacytic syndrome ... hematuria, H/A. diagnosis ... smear shown: no shistocytes ... maltese cross +burr cells ... and spur cells,
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
believed to be an autoinflammatory ... The diagnosis of ... Familial cold autoinflammatory ... , - Muckle–Wells ... #Diagnosis
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... considered an autoinflammatory ... neutrophils & T-cells ... #PG #clinical #photo