3 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... + lab signs of end ... cells releasing ... diagnosis #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Fibrinolysis → End ... Treat primary cause ... #treatment #management ... #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
TLS (tumor-lysis ... syndrome): - Hematologic ... G6PD first) DIC ... Treat underlying cause ... “big & sticky” cells