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diagnosis management differential hematology signs symptoms clinical video barre cns guillain hiv mds myelodysplastic ophthalmology rheumatology vasculitis workup als amyotrophic
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Hyperviscosity Syndrome ... of breath • Neurologic ... neutrophil count < 500 cells ... Hoarseness • Chest and ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... Lysis of tumor cells
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Caused commonly ... Pathophysiology: ... Treatment: anticholinergics ... pleurothotonus #PhysicalExam ... #clinical #neurology
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 Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic ... #Differential #Causes
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Paresthesias: Hands ... #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... diagnosis #hematology #oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
muscles: “myasthenic crises ... test - Cogan sign ... - Peek sign ... Myasthenia Crises ... diagnosis #management #neurology
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... experience, the cause ... or induced by treatment ... ophthalmology #physicalexam ... #neurology #Anisocoria
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 Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... the underlying cause ... • Treatment of ... until cause identified
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