13 results
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Pathophysiology ... Diagnosis: • Vasculitis ... #pulmonary #differential ... #causes #management
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
some red blood cells ... hemorrhage, and seizure activity ... epilepticus • Pathophysiology ... Edema: • Pathophysiology ... • Pathophysiology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... emboli • Lung abscess ... • HIV: 2/3 pulmonary ... Langerhans giant cells
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... hair follicles -> causes ... decr release and activity ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressing GN • New pulmonary ... Multinucleated giant cells ... MPO > PR3) • Pulmonary ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... signs/symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology ... for concomitant pulmonary
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... emboli • Lung abscess ... • HIV: 2/3 pulmonary ... Langerhans giant cells
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... muscarinic agonists • Active
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... symptoms are not caused ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary