24 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... #treatment #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Summary Epidemiology ... extrapulmonary cases ... symptoms of active pulmonary ... decreased reflexes Pathophysiology ... #Summary
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... Goodpasture's cause ... differential #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... - Erosions and crusts ... erosions in ~20% Management ... #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressing GN • New pulmonary ... Multinucleated giant cells ... MPO > PR3) • Pulmonary ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Summary Kawasaki ... the most common vasculitis ... , Cough • +/-Nausea ... #Disease #KD #vasculitis ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Summary Lung ... Lung Abscess Pathophysiology ... Diagnosis: • Vasculitis ... Lung #Abscess #pulmonary
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
CYTOPATHIC HYPOXIA - Cells ... Hypoxia #Hypoxemia #summary ... #pulmonary #differential ... #diagnosis #causes ... #pathophysiology