20 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... mutated in all cells ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Neuro-OphthaImoIogy - Visual Field Defects - Localization Map
 - Optic Nerve Lesion (Monocular vision loss)
 -
Neuro-OphthaImoIogy ... Pituitary/metastatic tumor ... NeuroOphthaImoIogy #Neurology #Differential ... #Diagnosis #Anatomy ... #Causes #Ophthalmology
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... • Neurologic symptoms ... • Aneurysm • Tumor ... #DoubleVision #Differential ... #Causes #Ophthalmology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... cells releasing ... Syndrome #TLS #diagnosis
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Lesion on X-Ray - Differential ... Diagnosis Algorithm ... Constitutional Symptoms ... BoneLesion #XRay #MSK ... #Orthopedics #Causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... predominant (LP) tumour ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... overload) Other Symptoms ... Fanconi syndrome • Tumor-induced ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - Differential ... Diagnosis Framework ... some red blood cells ... #differential # ... diagnosis #NCPE
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... are not caused ... anterior/posterior MSK
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Too many cells in ... delivery/sensing) vs tumor ... kidneys) - Some tumors ... #Polycythemia #Differential