21 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in all cells ... Retinoblastoma #pathophysiology ... #ophthalmology ... #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management ... #neurology #treatment
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... various inflammatory cells ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... poor nutrition Clinical ... Psychiatric symptoms ... nonimmune hemolysis MSK ... Treatment:
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... Syndrome #diagnosis #management ... #signs #symptoms
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... caucasian • Symptoms ... Unilateral • Signs ... - Typical MS-like ... #ophthalmology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... PO4 and Mg into cells ... Constipation - MSK ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
Pathogenesis and clinical ... -> The pelvis is ... #Scoliosis #pathophysiology ... #msk #diagnosis ... #signs #symptoms