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management differential hematology neurology disorders sclerosis symptoms als amyotrophic apml chf classification clinical criticalcare differentiation ecg electrocardiogram eosinophil eosinophilia equivalents
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... unless worrisome EKG ... #TLS #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Low BMI < 18.5 kg ... PO4 and Mg into cells ... Constipation - MSK ... #diagnosis #pathophysiology ... #symptoms #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... lesions) McDonald diagnostic ... Multiple Sclerosis Treatment ... management #neurology #treatment
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... Amy Chung, MD, MSc ... Classification #pathophysiology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... Prednisone 5mg/kg
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
segment at (or 40-60 ms ... point • De Winter syndrome ... V2 • Wellens sign ... #EKG #diagnosis ... #differential #cardiology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... column Treatment
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... (e.g. incidental ... anterior/posterior MSK ... #Management #Signs
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