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diagnosis oncology differential management algorithm biliary cell cholangitis chronic classification gap globulin hemeonc hemolytic hemophagocytic heon hepatorenal hlh hodgkins hrs
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
dullness, puddle sign ... incisional). 3) Signs ... Routine tests: Cell ... #workup #Differential ... #Diagnosis #hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... or basket cells ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... Consider sickle cell ... Diagnosis #Algorithm #workup ... #hematology #testing
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... failure PBC Signs ... cholangitis #diagnosis #workup ... #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... count (anemia) ... • Aplastic Anemia ... Workup: • Complete ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... classification #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Cytopenia, Other cell ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Liver disease: Cirrhosis ... gastric tumors • Hematology ... anemia • Other ... differential #diagnosis #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
MM, the plasma cell ... appearance Favored Sites ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... - Cytopenias (anemia ... Pathophysiology ... and CD8+ T cells ... Diagnosis #Management #Hematology
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