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diagnosis rheumatology management neurology lupus oncology pathology sle smear systemic differential disease hemolytic signs symptoms treatment vasculitis workup activation agglutinin
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Sickled red cells ... disease Bite cells ... Smear #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... Pathology #Smear #Microscopy ... #Hematology
Dysmorphic Red Blood Cells on Electron Microscopy This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... on Electron Microscopy ... ElectronMicroscopy #SEM #clinical ... #pathology #hematology ... #nephrology #Red
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 Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... polychromatophilic cells ... #Hematology #Pathology ... #Smear #Microscopy
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #SLE #CNS #neurology ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Constitutional Syndromes ... marrow-failure syndromes ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... Clinical Features ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... ) Blood (75%): Anemia ... SLE #systemic #erythematosus ... symptoms #diagnosis #rheumatology
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