15 results
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... on Electron Microscopy ... dysmorphic red blood cells ... from the urine ... clinical #pathology #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... decreased reflexes Pathophysiology ... of AFB by smear microscopy ... Management: ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (MDR-TB ... tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (MDR-TB ... tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... chlorambucil) 2) Purine ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Schistocytes, helmet cells ... causes #treatment #management ... #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Pleocytosis > 100 cells ... , Hep A/B/CMV, TB ... Myelitis #diagnosis #management