33 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology ... Mechanisms #DOAC #Hematology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... respiratory distress syndrome ... #Pharmacology # ... Management #Treatment ... #Indications
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... TPO, TPO-RA • Infections ... : Chronic infections
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... risk-stratification • Risks: infection ... only curative treatment ... #hematology #oncology
Pharmacologic Treatment of Hypertensive Emergencies in Pregnancy
Drug - Dose range - Onset/oeak/duration - Side effects
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Pharmacologic Treatment ... hypotension, lupus-like syndrome ... , warmth along injection ... Obstetrics #OBGyn #HTN #Pharmacology ... #Medications
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... - Antithyroid medications ... Idiopathic • Infections ... aplastic anemia Treatment ... Anemia #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
variable tremor, mask ... reduction; change medication ... tremor ("rabbit syndrome ... months or years of treatment ... #SideEffects #pharmacology