33 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
and induce mast cell ... plasma cells that ... complexes bind to mast cells ... • Inflammatory cells ... #Immunology #pathophysiology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Bell's Palsy Bell ... Bell’s palsy happens ... By @rev.med #Bells ... #Palsy #neurology ... #anatomy #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antibodies bind to mast cells ... with cytotoxic T cells ... natural killer cells ... antigen - TH1 cells ... and cytotoxic T cells
Innate Immune Cells - Pathophysiology
The innate immune system consists of granulocytes, mast cells, natural killer cells,
Innate Immune Cells ... granulocytes, mast cells ... natural killer cells ... Monocytes and B-cells ... proteins to T-cells
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
surfaces of body cells ... -> B-Cells with ... foreign -> B-cells ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... TH2 cells also migrate ... eosinophils, mast cells ... submucosal mast cells
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... responses, and B cells ... antigen activates B cells ... to cytotoxic T cells ... #pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
-> Helper T cells ... producing Plasma Cells ... Abs coat mast cells ... to lgE on mast cells ... of inflammatory cells
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Ag-presenting cells ... CD4+ helper T cells ... or plasma cells ... Humoral #Immunity #pathophysiology ... #immunology