18 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... Stevens-Johnson Syndrome ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... Transcellular Shift Into Cells ... imports K+ into cells ... - Refeeding Syndrome ... potassium #low #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
maturation of B cells ... from precursor cells ... Absence of mature B cells ... CD19+) and plasma cells ... #immunology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... pattern of spread, B symptoms ... Classification #pathophysiology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Differential Diagnosis Algorithm ... Redistribution/ Shift into cells ... ), Hungry bone syndrome ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... Lysis of tumor cells
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... PO4 and Mg into cells ... #diagnosis #pathophysiology ... #symptoms #signs
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... .2>5 red blood cells ... #Algorithm #differential ... #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... • Induce blast cell ... Diagnosis: >3 symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter cell-mediated ... various inflammatory cells ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... Diagnosis #Signs #Symptoms