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management differential algorithm blood hematology hyperkalemia hypokalemia neurology product reactions treatment agammaglobulinemia als amyotrophic gitelman high hypersensitivityreaction k lateral low
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift Into Cells ... imports K+ into cells ... #potassium #low ... #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... 7) - principal cells ... #Algorithm #causes ... #potassium #high ... #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... maturation of B cells ... from precursor cells ... CD19+) and plasma cells ... #immunology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... - Causes progressive ... between nerve cells
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Management Summary Causes ... kidney tubular cells ... Monitor potassium ... #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... only if no clear cause ... Drives K+ into cells ... Management #Treatment #potassium ... #nephrology #K
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... Pleocytosis > 100 cells ... #management #neurology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Allergic reaction ... Causes purpura & ... products contain potassium ... from lysed cells ... #Transfusion #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... products contain potassium ... from lysed cells ... #Transfusions #diagnosis
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