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allergy diagnosis hypersensitivityreaction management aids apml associated dementia differentiation disorder follicularphase gitelman hand hematology hiv hypokalemia menstrualcycle neurocognitive neurology oncology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis: Pathogenesis ... Anaphylaxis is ... of inflammatory cells ... #pathophysiology ... #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... Stevens-Johnson Syndrome ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
allergen-specific plasma cells ... complexes bind to mast cells ... • Inflammatory cells ... conjunctivitis • Anaphylaxis ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained Early Follicular Phase (Days 0-5) • Granulosa cells
• Granulosa cells ... receptors on granulosa cells ... ) • Granulosa cells ... and granulosa cells ... Polycystic Ovarian Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... PE, DAH, CHF, Anaphylaxis ... Differentiation #Syndrome
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... invades mononuclear cells ... CNS ○ Infected cells ... The clinical syndrome ... dementia #AIDS #Neurology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... apical membrane of cells ... #diagnosis #nephrology ... #management #pathophysiology
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