37 results
Bell's palsy
There are many different causes of Facial Nerve Palsy. However, the commonest
cause of unilateral facial
Bell's palsy There ... variety known as Bell's ... - Ptosis #Bells ... #Signs #Symptoms ... #Diagnosis
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... TH2 cells also migrate ... #asthma #pathophysiology ... immunology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
of T-helper & inflammatory ... cells) Clinical ... • Neurologic: Bell's ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Natural Killer Cells ... cell activity #Inflammatory ... #Inflammation #pathophysiology ... #immunology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
production of inflammatory ... Recruitment of inflammatory ... cells • ANS activation ... #Anaphylaxis #pathophysiology ... #immunology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... the epidermis 2) Inflammatory ... germinative skin cells ... Skin-homing T-cells
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
allergen-specific plasma cells ... complexes bind to mast cells ... cells recruited ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... maturation of B cells ... from precursor cells ... CD19+) and plasma cells ... #immunology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter inflammatory ... yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T cells ... natural killer cells ... activation provides inflammatory ... Classification #Pathophysiology ... #Allergy #Diagnosis