32 results
Bell's palsy
There are many different causes of Facial Nerve Palsy. However, the commonest
cause of unilateral facial
Bell's palsy There ... variety known as Bell's ... - Ptosis #Bells ... #Palsy #Neurology ... #Signs #Symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
of T-helper & inflammatory ... cells) Clinical ... • Neurologic: Bell's ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... TH2 cells also migrate ... #asthma #pathophysiology ... immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Natural Killer Cells ... cell activity #Inflammatory ... #Inflammation #pathophysiology ... #immunology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter inflammatory ... yrs old; F>M Signs ... /Symptoms: - Fever ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
production of inflammatory ... Recruitment of inflammatory ... cells • ANS activation ... #Anaphylaxis #pathophysiology ... #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
maturation of B cells ... from precursor cells ... /Symptoms/Findings ... CD19+) and plasma cells ... #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
allergen-specific plasma cells ... complexes bind to mast cells ... cells recruited ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... cytokines -> localized inflammatory ... removal of these cells ... #diagnosis #signs ... #symptoms #complications