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diagnosis management neurology oncology treatment anemia hemophagocytic hlh lymphohistiocytosis pathology agglutinin aids anatomy aplastic apml associated autoinflammatory bells bloodcells causes
Bell's Palsy Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
unknown but its clinically ...     - Epstein-Barr ... By @rev.med #Bells ... #Palsy #neurology ... #anatomy #pathophysiology
Dysmorphic Red Blood Cells on Electron Microscopy This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... dysmorphic red blood cells ... ElectronMicroscopy #SEM #clinical ... #pathology #hematology ... #nephrology #Red
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 VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... hematopoietic stem cells ... blood myeloid cells ... Autoinflammatory #Somatic #rheumatology
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... Smear #Microscopy #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... Anemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... accumulation of clinical ... treatment #summary #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... CSF white blood cell ... the underlying pathophysiology ... #Syndrome #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... • Induce blast cell ... diagnosis #management #hematology
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