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management differential neurology hematology classification oncology aids causes guillain hemeonc hepatology acidosis acute allergy amyotrophic anemia aplastic apml associated chloride
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Campylobacter jejuni - HIV ... #Syndrome #diagnosis ... #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... CMV) • Epstein-Barr ... number of CD34+ cells ... Number of CD34+ cells
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells ... #TLS #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... B symptoms not as ... Classification #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... intestines, white blood cells
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... invades mononuclear cells ... CNS ○ Infected cells ... Diagnosis: MRI ... The clinical syndrome
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
IgG can also mediate ... erythematosus Type IV ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Syndrome #diagnosis
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
• Presents as ... decrease (<200 cells ... DDX: • Epstein-Barr ... antibody test) Treatment ... #HIV #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Infection - Viral (HIV ... kidney tubular cells ... per day until stable ... #nephrology
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